Link: http://www.nytimes.com/2016/06/05/opinion/sunday/are-opioids-the-next-antidepressant.html?partner=bloomberg&_r=1 

By Anna Fels
June 4, 2016

ONE of the most painful experiences of being a psychiatrist is having a patient for whom none of the available therapies or medications work.

A while back, I was asked to do a consultation on just such a patient. This person had been a heroin addict in her early 20s. She had quit the opioid five years earlier, but her life was plagued with anxiety, apathy and self-doubt that prior treatments had not helped. At the end of the session, almost as an afterthought, she noted with irony that the only time in her adult life when she had been able to socialize easily and function at work was when she had been hooked on heroin.